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Psalm 22

Sal. 22:21 KJV (With Strong’s)

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21
Save
yasha` (Hebrew #3467)
properly, to be open, wide or free, i.e. (by implication) to be safe; causatively, to free or succor
KJV usage: X at all, avenging, defend, deliver(-er), help, preserve, rescue, be safe, bring (having) salvation, save(-iour), get victory.
Pronounce: yaw-shah'
Origin: a primitive root
me from the lion’s
'ariy (Hebrew #738)
from 717 (in the sense of violence); a lion
KJV usage: (young) lion, + pierce (from the margin).
Pronounce: ar-ee'
Origin: or (prolonged) earyeh {ar-yay'}
h mouth
peh (Hebrew #6310)
the mouth (as the means of blowing), whether literal or figurative (particularly speech); specifically edge, portion or side; adverbially (with preposition) according to
KJV usage: accord(-ing as, -ing to), after, appointment, assent, collar, command(-ment), X eat, edge, end, entry, + file, hole, X in, mind, mouth, part, portion, X (should) say(-ing), sentence, skirt, sound, speech, X spoken, talk, tenor, X to, + two-edged, wish, word.
Pronounce: peh
Origin: from 6284
: for thou hast heard
`anah (Hebrew #6030)
properly, to eye or (generally) to heed, i.e. pay attention; by implication, to respond; by extens. to begin to speak; specifically to sing, shout, testify, announce
KJV usage: give account, afflict (by mistake for 6031), (cause to, give) answer, bring low (by mistake for 6031), cry, hear, Leannoth, lift up, say, X scholar, (give a) shout, sing (together by course), speak, testify, utter, (bear) witness. See also 1042, 1043.
Pronounce: aw-naw'
Origin: a primitive root
me from the horns
qeren (Hebrew #7161)
a horn (as projecting); by implication, a flask, cornet; by resembl. an elephant's tooth (i.e. ivory), a corner (of the altar), a peak (of a mountain), a ray (of light); figuratively, power
KJV usage: X hill, horn.
Pronounce: keh'-ren
Origin: from 7160
of thei unicorns
r'em (Hebrew #7214)
or reym {rame}; or rem {rame}; from 7213; a wild bull (from its conspicuousness)
KJV usage: unicorn.
Pronounce: reh-ame'
Origin: or rieym {reh-ame'}
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Cross References

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Ministry on This Verse

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me from.
horns.
 Finally in the first part of verse 21, it is the power of the devil the Lord has to meet. (Psalms 21 by H. Smith)
 (vs. 21 B) Thus every form of suffering has been endured―the enmity of the Jews, the shameless opposition of the Gentiles, the malice of Satan, and above all the forsaking of God when making atonement. Then when all is over, when the great work of atonement is accomplished, and the extreme point of suffering is reached, set forth by the horns of the buffaloes, the cry of the Sufferer is heard, and the answer comes. Christ can say, “Thou hast heard me.” (Psalms 21 by H. Smith)

J. N. Darby Translation

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21
Save me from the lion’s mouth. Yea, from the horns of the buffaloes hast thou answered meb.

JND Translation Notes

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b
Or "Answer me."