Vine of Sodom

Concise Bible Dictionary:

Many suggestions have been made as to what tree this refers to. Josephus speaks of some fruits that grew near the Dead Sea, which have a color as if fit to be eaten, but if plucked they dissolve into smoke and ashes.” Many have sought for such fruit. Some judge the vine alluded to in scripture to be the poisonous colocynth, which grows near the Dead Sea. May not the term be symbolical of that which leads to destruction, which was the doom of Sodom? (Deut. 32:3232For their vine is of the vine of Sodom, and of the fields of Gomorrah: their grapes are grapes of gall, their clusters are bitter: (Deuteronomy 32:32)).