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Isaiah 21

Isa. 21:1 KJV (With Strong’s)

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1
The burden
massa' (Hebrew #4853)
a burden; specifically, tribute, or (abstractly) porterage; figuratively, an utterance, chiefly a doom, especially singing; mental, desire
KJV usage: burden, carry away, prophecy, X they set, song, tribute.
Pronounce: mas-saw'
Origin: from 5375
of the desert
midbar (Hebrew #4057)
a pasture (i.e. open field, whither cattle are driven); by implication, a desert; also speech (including its organs)
KJV usage: desert, south, speech, wilderness.
Pronounce: mid-bawr'
Origin: from 1696 in the sense of driving
of the sea
yam (Hebrew #3220)
a sea (as breaking in noisy surf) or large body of water; specifically (with the article), the Mediterranean Sea; sometimes a large river, or an artifical basin; locally, the west, or (rarely) the south
KJV usage: sea (X -faring man, (-shore)), south, west (-ern, side, -ward).
Pronounce: yawm
Origin: from an unused root meaning to roar
. As whirlwinds
cuwphah (Hebrew #5492)
a hurricane
KJV usage: Red Sea, storm, tempest, whirlwind, Red sea.
Pronounce: soo-faw'
Origin: from 5486
d in the south
negeb (Hebrew #5045)
the south (from its drought); specifically, the Negeb or southern district of Judah, occasionally, Egypt (as south to Palestine)
KJV usage: south (country, side, -ward).
Pronounce: neh'-gheb
Origin: from an unused root meaning to be parched
pass
chalaph (Hebrew #2498)
properly, to slide by, i.e. (by implication) to hasten away, pass on, spring up, pierce or change
KJV usage: abolish, alter, change, cut off, go on forward, grow up, be over, pass (away, on, through), renew, sprout, strike through.
Pronounce: khaw-laf'
Origin: a primitive root
through; so it cometh
bow' (Hebrew #935)
to go or come (in a wide variety of applications)
KJV usage: abide, apply, attain, X be, befall, + besiege, bring (forth, in, into, to pass), call, carry, X certainly, (cause, let, thing for) to come (against, in, out, upon, to pass), depart, X doubtless again, + eat, + employ, (cause to) enter (in, into, -tering, -trance, -try), be fallen, fetch, + follow, get, give, go (down, in, to war), grant, + have, X indeed, (in-)vade, lead, lift (up), mention, pull in, put, resort, run (down), send, set, X (well) stricken (in age), X surely, take (in), way.
Pronounce: bo
Origin: a primitive root
from the desert
midbar (Hebrew #4057)
a pasture (i.e. open field, whither cattle are driven); by implication, a desert; also speech (including its organs)
KJV usage: desert, south, speech, wilderness.
Pronounce: mid-bawr'
Origin: from 1696 in the sense of driving
, from a terrible
yare' (Hebrew #3372)
to fear; morally, to revere; caus. to frighten
KJV usage: affright, be (make) afraid, dread(-ful), (put in) fear(-ful, -fully, -ing), (be had in) reverence(-end), X see, terrible (act, -ness, thing).
Pronounce: yaw-ray'
Origin: a primitive root
land
'erets (Hebrew #776)
the earth (at large, or partitively a land)
KJV usage: X common, country, earth, field, ground, land, X natins, way, + wilderness, world.
Pronounce: eh'-rets
Origin: from an unused root probably meaning to be firm
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Cross References

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Ministry on This Verse

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1-10:  The prophet, bewailing the captivity of his people, sees in a vision the fall of Babylon by the Medes and Persians.
11-12:  Edom, scorning the prophet, is moved to repentance.
13-17:  The set time of Arabia's calamity.
The burden.The first ten verses of this chapter contain a prediction of the taking of Babylon by the Medes and Persians; which is here denominated "the desert of the sea," because the country around it, and especially towards the sea, was a great morass, often overflowed by the Tigris and Euphrates, and only rendered habitable by being drained by a number of canals.
the desert.
As whirlwinds.
from.
 In chapter 21 we return to the doom of Babylon. It is to be “the desert of the sea.” In Jeremiah’s prophecy against the city he says, “The sea is come up upon Babylon” (51:42), which helps to explain the expression. Babylon would be swamped by the sea of nations and become a desert. (Isaiah 21 by F.B. Hole)

J. N. Darby Translation

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1
The burden of the desert of the seac. As whirlwinds in the southd pass through, so it cometh from the desert, from a terrible land.

JND Translation Notes

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c
i.e. Babylon.
d
Negeb. see Gen. 12.9.