This title is susceptible of considerable latitude of meaning and has various applications in scripture.
1. There were “sons of God” who took wives of “the daughters of men” (Gen. 6:44There were giants in the earth in those days; and also after that, when the sons of God came in unto the daughters of men, and they bare children to them, the same became mighty men which were of old, men of renown. (Genesis 6:4)). These are believed by some to have been angels, permitted to take human form: (compare Jude 6-76And the angels which kept not their first estate, but left their own habitation, he hath reserved in everlasting chains under darkness unto the judgment of the great day. 7Even as Sodom and Gomorrha, and the cities about them in like manner, giving themselves over to fornication, and going after strange flesh, are set forth for an example, suffering the vengeance of eternal fire. (Jude 6‑7)). Others judge the descendants of Seth to be alluded to.